The Chronic Respiratory Disease Questionnaire (CRQ) is the most commonly used disease specific measurement tool to assess HRQL in patients with chronic . Due to their widespread and thorough validation, the following questionnaires are recommended: Chronic Respiratory Disease Questionnaire (CRDQ or CRQ) . To measure health related quality of life in patients with chronic respiratory disease.

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Author information Copyright and License information Disclaimer. The 3 studies included: Assessing the minimal important differences in symptoms: Initial testing of reproducibility, responsiveness, and validity was also completed.

However, correlations between the CRQ and other specific measures of pulmonary disease were found to be significantly questionnairw than correlations with generic measures.

Chronic Respiratory Disease Questionnaire-CRQ

These changes might be missed if physiological measures are used alone. Many studies reported internal consistency of the questionnaire to be high over all domains 391319 with Cronbach’s alpha coefficients ranging from 0. Other applications, please complete the request form at http: Support Center Support Center.

This degree of test-retest reliability has been shown for both the individualized and standardized forms of the CRQ.

Chronic Respiratory Disease Questionnaire (CRQ)

The limited availability of literature regarding intra-rater and inter-rater reliability indicates the need for further research in these areas. There was good agreement between the predicted and actual correlations in both these cases.

Comparison of discriminative properties among disease-specific questionnaires quuestionnaire measuring health-related quality of life in patients with chronic obstructive pulmonary disease. National Center for Biotechnology InformationU. Prentice Hall Health; Although the authors determined that the self-administered version of the CRQ perceives analogous levels of mastery, emotional qestionnaire, and fatigue, they state that the different versions of the test should not be used interchangeably.


In the first assessment, the tool was administered to 13 patients all diagnosed with chronic lung disease and the patients were then reassessed 2 to 6 weeks later chrinic treatment had been initiated. They also found that the baseline scores for the self-reported test were significantly lower across all domains than for the interviewer-administered questionnaire.

In both studies, queztionnaire CRQ was used to evaluate patients who were predicted to improve with initiation or modification of treatment. All questions were pretested to finalize structure and wording.

Limitations to its use in the clinic might include cost and the time required for administration. The original interviewer administered CRQ requires 20 to 25 minutes for the first administration and 10 to 15 minutes for each follow up visit.

Generic and specific measurement of chronif quality of life in a clinical trial of respiratory rehabilitation. The CRQ is available in four different formats approximate time needed for the first administration:.

This validated and reliable tool is widely used to measure health related quality of life in patients with chronic airflow limitations. List per page or see all. In the fatigue domain, which was not reliable as a whole, 3 of the 4 individual items showed insignificant correlation. In studies of the CRQ, mean patient age has typically been reported around 67 years; 31112 however, patients as young as 35 have been studied.

CRQ – Chronic Respiratory Disease Questionnaire

One hundred twelve patients participated in the study. This article has been cited by other articles in PMC. Guyatt’s study illustrates that the CRQ has adequate responsiveness to detect highly significant differences, even within small numbers of subjects.

There is currently no gold standard for determining HRQL, 20 so the validity of the CRQ has been assessed primarily through construct and convergent validity. The original version of the CRQ was developed in by Guyatt et al 2 and followed Kirshner and Guyatt’s 7 principles of questionnaire development. Again, considerable improvements in the scores were seen in all domains of the original version. Measuring functional status in chronic lung disease: Aaron et al 14 used the responsiveness statistic to assess the sensitivity.


High response rates to this type of questionnaire have been achieved in outpatient settings; however, the interview form is quite expensive 13 and time consuming.

Validity and reliability of a quality-of-life instrument: Functional measures were also well correlated with CRQ change scores. Measurement of health status: Six minute walk test scores, however, were found to be only weakly correlated with all domains of the CRQ.

The resulting questionnaire contains 20 items that are believed to represent areas of dysfunction that are most significant to this patient population. The CRQ is available in four different formats approximate time needed for the first administration: Validity was determined to be strong; no statistically significant difference between the 2 instruments was found in the fatigue and mastery domains, and the small mean differences found in the dyspnea 0.

It has been used extensively in research and clinical trials since Construct validity was maximized during the original development of the questionnaire by using a multistep process to determine and incorporate the significant aspects of HRQL that are affected by pulmonary disease.

Test-retest reliability of the CRQ has been found to be high. Construct validity refers to an instrument’s ability to measure the constructs, or abstract concepts, that it intends to measure.

The developers suggest that the CRQ be used both in clinical research and in clinical practice to monitor changes in HRQL in patients with chronic respiratory disease.